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Freq.: Quarterly

eISSN: 2251-7308 
pISSN: 2228-5881 

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Review Article

Next-Generation mRNA Cancer Vaccines: Integrating Innovative Delivery Systems, Personalized Antigen Discovery, and Future Clinical Strategies
Maryam Mashhadi Abolghasem Shirazi* ORCID
Adv Pharm Bull. doi: 10.34172/apb.46663 | Published on: 2026 Jul 14
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Research Article

Redox-mediated sensitization of melanoma cells to Vemurafenib by cold atmospheric plasma: A molecular insight into apoptotic and autophagic regulation
Zahra Yazdani ORCID, Farshad Sohbatzadeh, Saeid Abediankenari, Monireh Golpour, Sadegh Fattahi, Alireza Rafiei* ORCID
Adv Pharm Bull. doi: 10.34172/apb.46838 | Published on: 2026 Jul 12
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Research Article

Development of a flow cytometric immunoassay using recombinant vascular endothelial growth factor (VEGF)-functionalized poly(ε-caprolactone) microbeads for bevacizumab quantification
Negar Namaei-Ghasemnia ORCID, Mohammad Rabiee* ORCID, Fatemeh Davami* ORCID, Yeganeh Talebkhan-Garoosi ORCID, Mohamad Ghorbani ORCID
Adv Pharm Bull. doi: 10.34172/apb.46777 | Published on: 2026 Jul 12
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Research Article

Anti-Apoptotic Effects of Sericin in Lumbar Canal Stenosis-Induced Underactive Bladder Model
Sakineh Hajebrahimi ORCID, Nasrin Abolhasanpour ORCID, Hadi Mostafaei, Fateme Tahmasbi, Javad Mahmoudi* ORCID, Hanieh Salehi-Pourmehr* ORCID
Adv Pharm Bull. doi: 10.34172/apb.46989 | Published on: 2026 Jul 11
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Research Article

Protodioscin Restores Ovarian Function and Suppresses p53–Bax/Bcl-2–Mediated Apoptosis in a Doxorubicin-Induced Model of Ovarian toxicity
Amoura M. Abou-El-Naga ORCID, Aya M. Abd-Elhady, Mohamed E. Abdraboh ORCID, Yasmin M. Tag, Maher Monir Akl* ORCID
Adv Pharm Bull. doi: 10.34172/apb.46593 | Published on: 2026 Jul 11
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Research Article

Development of Spray-Dried Enteric Omeprazole Microparticles Using O-Carboxymethyl Chitosan and Eudragit® S100: Central composite Design Optimization and In Vitro-In Vivo evaluation
Hamid Reza Arabloo ORCID, Homa Faghihi ORCID, Melika Kiani ORCID, Fatemeh Khonsari ORCID, Mahdi Gholami, Fatemeh Atyabi* ORCID
Adv Pharm Bull. doi: 10.34172/apb.47194 | Published on: 2026 Jul 01
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Research Article

Effects of Ketogenic Diet on Neuropeptides (Kisspeptin and Phoenixin-14) in Obese Polycystic Ovarian Syndrome

Talib Hussein Abdullah* ORCID, Diana Hussein Abdullah, Malik Musa Sultan ORCID
Adv Pharm Bull. doi: 10.34172/apb.47249 | Published on: 2026 Jul 01
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Research Article

pH-Sensitive Folate-Targeted Liposomal Vitamin D Reprograms EZH2/STAT3 Axis and Induces Apoptosis, ROS, and Autophagy in MCF-7 Breast Cancer Cells
Soheil Abbaspour-Ravasjani ORCID, Rahim Shahvalizadeh ORCID, Malahat Safavi ORCID, Mina A frashteh Nour ORCID, Mahdi Talebi ORCID, Maryam Mohammadi, Hamed Hamishehkar* ORCID
Adv Pharm Bull. doi: 10.34172/apb.46791 | Published on: 2026 Jul 01
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Review Article

Radiotheranostics and the Future of Cancer Therapy: Harnessing Combination Strategies and AI
Ayad H. Hasan ORCID, Mohammadreza Azimi ORCID, Tola Abdulsattar Faraj, Nazila Biglari, Nazanin Musapour, Sadaf safaei ORCID, Houman Torabian Basmen ORCID, Soran K. Najmaldin, Zahrah Mohammed Maghdid, Mostafa kashani* ORCID, Vesal Firoozi ORCID
Adv Pharm Bull. doi: 10.34172/apb.47174 | Published on: 2026 Jul 01
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Review Article

Lipid-Based Nanocarriers for Acne Treatment: Current Progress and Clinical Feasibility
Ayda Rajabi ORCID, Azizeh Rahmani Del Bakhshayesh, Leila Hosseini, Azizeh Farshbaf-khalili, Halimeh Amirazad, Amélia C. F. Vieira, Soraya Babaie* ORCID, Ana Cláudia Paiva-Santos
Adv Pharm Bull. doi: 10.34172/apb.47085 | Published on: 2026 Jul 01
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Research Article

Autophagy modulation influenced the spermatogenesis in rodent testicular organoids and diabetic condition
Shadi Atazadeh ORCID, Maryam Hasan Sadeh, Farah Farokhi, Shahin Ahmadian, Sepideh Saghati, Fereshteh Valipour, Amir Fattahi, Amin Tamadon, Reza Rahbarghazi, Mahdi Mahdipour* ORCID
Adv Pharm Bull. doi: 10.34172/apb.46240 | Published on: 2026 Jun 29
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Research Article

Exploring Siglec-7 expression and apoptosis rates in platelet concentrates under various storage conditions
Asra Amelirad ORCID, Davoud Pashoutan Sarvar ORCID, Parvin Akbarzadehlaleh ORCID, Karim Shamsasenjan* ORCID
Adv Pharm Bull. doi: 10.34172/apb.47163 | Published on: 2026 Jun 29
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Mini Review

Development of Cloned B Cell Populations as Immunotherapeutic Agents Against Myc Carcinogenic Proteins
Manisha S Lalan* ORCID, Sushrut S Joshi, chitrali S Talele, Guno Sindhu Chakraborthy, Sachin Mali
Adv Pharm Bull. doi: 10.34172/apb.46527 | Published on: 2026 Jun 29
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Research Article

Investigating the Radioprotective Properties of C60 Fullerene Nanoparticles: Effects on Adipose-Derived Stem Cell Viability and Inflammatory Markers
Golnoosh Goodarzi Fard ORCID, Arash Abdolmaleki* ORCID, Asadollah Asadi, Farhad Zolfagharpour, Ezzat Nourizadeh, Aida Nahumi, Hussein A. Ghanimi
Adv Pharm Bull. doi: 10.34172/apb.46954 | Published on: 2026 Jun 29
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Research Article

Comparative Analysis of MAR and Terminator Elements in Controlling Stable EPO Expression in CHO-K1 Cells
Fatemeh Jalali* ORCID, Shahriyar Abdoli, Fatemeh Shamsabadi, Ahad Yamchi, Anvarsadat Kianmehr, Majid Shahbazi* ORCID
Adv Pharm Bull. doi: 10.34172/apb.45955 | Published on: 2026 Jun 29
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Research Article

Royal Jelly-Loaded LDH Nanostructures: A Novel Topical Therapy for Atopic Dermatitis via Inflammasome Suppression in Mice
Fardin Khajepour ORCID, Mehdi Ranjbar, Merat Mahmoodi, Nasrin Bazargan, Fatemeh Mohammadi Henjeroei, Muhammad Hossein Ashoub, Reza Nosratabadi ORCID
Adv Pharm Bull. doi: 10.34172/apb.46710 | Published on: 2026 Jun 29
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Review Article

Interplay between endolysosomal calcium signalling, EMT, and autophagy in colorectal cancer (CRC): Implications for metastasis and therapeutic strategies.
Nur Aqilah Nadhirah Affendie ORCID, Nurul Syahmin Ab Aziz, Siti Yusrina Nadihah Jamaludin ORCID, Normala Abd Latip ORCID, Aisyah Hasyila Jahidin* ORCID
Adv Pharm Bull. doi: 10.34172/apb.45688 | Published on: 2026 Jun 29
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Research Article

Sericin improves cognitive outcomes in a mouse model of cerebral ischemia: The role of Blood-Brain Barrier disruption and edema
Leila Hosseini ORCID, Seyed Mehdi Vatandoust, Narmin Farazi, Amir Pasokh, Saeed Sadigh-Eteghad, Mohammad Farzipour, Fereshteh Farajdokht, Alireza Mohajjel Nayebi, Ali Hassanzadeh, Javad Mahmoudi ORCID
Adv Pharm Bull. doi: 10.34172/apb.46668 | Published on: 2026 Jun 29
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Research Article

Inducing collagen synthesis by a combination of an integrin receptor-stimulating collagen-based peptide and Chlorella vulgaris extract
Marjan Gholami ORCID, Seyed Shahriar Arab, Mehrdad Behmanesh* ORCID
Adv Pharm Bull. doi: 10.34172/apb.46552 | Published on: 2026 Jun 29
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Mini Review

Wound Healing and Nanotechnology: Recent Advances and Future Perspectives
Solmaz Ghaffari* ORCID, maryam Hassan ORCID
Adv Pharm Bull. doi: 10.34172/apb.47125 | Published on: 2026 Jun 28
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Research Article

Restoration of the PINK1/Parkin/PGC-1α axis by Liraglutide and Pravastatin co-therapy mitigates Doxorubicin-induced cardiotoxicity
Nada Monir Emad ORCID, Omneya Galal ORCID, Azza Said Awad ORCID, Hala Fahmy Zaki ORCID, Mona Magdy Saber* ORCID
Adv Pharm Bull. doi: 10.34172/apb.46963 | Published on: 2026 Jun 23
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Research Article

Coenzyme Q10 as a promising supplement for traumatic brain injury: a randomized, double-blind, placebo-controlled study
Mahdi Saghiriganjeh ORCID, Bahareh Hakiminia* ORCID, Bahador Bagheri ORCID, Keyhan Poorali ORCID, Ehsan Hosseinzadeh ORCID, Sara Salarian ORCID
Adv Pharm Bull. doi: 10.34172/apb.47049 | Published on: 2026 Jun 23
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Review Article

Chlorotoxin: A Scorpion Venom-Derived Peptide for Targeted Glioma Therapy and Imaging
Majid Jafari-Sabet* ORCID, Mohammad-Sadegh Lotfi
Adv Pharm Bull. doi: 10.34172/apb.47159 | Published on: 2026 Jun 22
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Research Article

The Effect of Wheat Adventitious Root and Callus Extracts on Protecting Skin Fibroblast Cells against Ultraviolet B
Hamed Hamishehkar* ORCID, Azam Salmasi, Sajjad Sedaghat, Parviz Abroumand Azar, Morteza Kosari Nasab
Adv Pharm Bull. doi: 10.34172/apb.47136 | Published on: 2026 Jun 17
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Original Article

Combination therapy of cisplatin and naturally induced exosomes from treated HeLa cells: A novel drug-free strategy for cervical cancer treatment
Sanaz Aghajani ORCID, Nasim Vousooghi, Abbas Hajifathali, Iman Seyhoun, Javad Verdi* ORCID
Adv Pharm Bull. doi: 10.34172/apb.46428 | Published on: 2026 Jun 15
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Editorial

Translational Landscape of Nanopharmaceuticals: Progress and Prospects on Biomacromolecule Delivery and Active Targeting
Azam Safary ORCID, Mostafa Akbarzadeh-Khiavi* ORCID
Adv Pharm Bull. doi: 10.34172/apb.47355 | Published on: 2026 Jun 15
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Research Article

Design, Characterization, and In-Vitro Targeted Delivery of Melatonin via pH-Responsive Niosome Nanoparticles Decorated with Folate Against Colon Cancer Cells
Davoud Jafari-Gharabaghlou ORCID, Urjwan Alali, Fadhil Jawad Al-Tu’ma, Hamid Babavalian, Mozafar Mohammadi, Mohammad Sadegh Hashemzadeh* ORCID
Adv Pharm Bull. doi: 10.34172/apb.46393 | Published on: 2026 Jun 01
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Letter to Editor

Gut microbiome influences the efficacy of neuropsychiatric drugs
Anjal Mohamed Ageel ORCID, Kannan Subbaram* ORCID, Sheeza Ali ORCID, Queen Alice Arul ORCID
Adv Pharm Bull. doi: 10.34172/apb.47093 | Published on: 2026 Jun 01
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Research Article

Bifunctional EGFR/CD44-Targeted Diabody-Decorated Doxorubicin-Loaded Solid Lipid Nanoparticles for Targeted Therapy in Triple-Negative Breast Cancer
Meysam Soleimani Badie ORCID, Melika Arastehfar, Katayoun Derakhshandeh* ORCID
Adv Pharm Bull. doi: 10.34172/apb.45929 | Published on: 2026 Jun 01
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Research Article

YKL-40-loaded amniotic fluid exosomes promoted angiogenesis response in a rat model of acute myocardial infarction
Hamid Lotfimehr ORCID, Narges Mardi, Reza Rahbarghazi* ORCID, Mohammad Nori, Shahram Rabbani
Adv Pharm Bull. doi: 10.34172/apb.46571 | Published on: 2026 May 25
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Review Article

Advances in Targeted Therapies for Head and Neck Cancer Using Polymer-based Nanoparticles
Mina Afrashteh Nour ORCID, Maryam Kouhsoltani* ORCID, Hamed Hamishehkar* ORCID
Adv Pharm Bull. doi: 10.34172/apb.45968 | Published on: 2026 May 24
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Review Article

Advanced electrochemiluminescence DNA aptasensor for sensitive detection of cancer biomarkers
Golnoush Rahvar ORCID, Mahdis Ojaghlou, Kimia Rostami, Mansour Mahmoudpour, Zahra Karimzadeh* ORCID
Adv Pharm Bull. doi: 10.34172/apb.47032 | Published on: 2026 May 24
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Systematic Review

Molecular And Clinical Significance of PDGFR Family in Papillary Thyroid Cancer: A Systematic Review
Atiyeh Dabouian ORCID, Roya Ghafoury, Mahboobeh Nazari, Omolbanin Asadi Ghadikolaeidi, Mohammad E. Khamseh*, sara cheraghi* ORCID
Adv Pharm Bull. doi: 10.34172/apb.46975 | Published on: 2026 May 24
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Research Article

Application of electrospun polycaprolactone/gelatin/layered double hydroxide/hymercromone in the death of melanoma cancer cells
fatemeh morad ORCID, tahereh foroutan* ORCID, seyedeh sara shafiei
Adv Pharm Bull. doi: 10.34172/apb.46964 | Published on: 2026 May 24
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Review Article

PLGA based “Lipid-Polymer Hybrid Nanoparticles”: A Convergent Platform of Active and Targeted Drug Delivery
Rajlaxmi Patro ORCID, Ch. Niranjan Patra, Subrata Mallick* ORCID
Adv Pharm Bull. doi: 10.34172/apb.46136 | Published on: 2026 May 23
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Research Article

Effect of Exosome-loaded hsa-miR-203a-3p on Triple Negative Breast Cancer Cell Viability, Migration, and Gene Targets: In Silico and In Vitro Study
Syamsul Arif Ardiansyah* ORCID, Sofia Mubarika Haryana* ORCID, Habibullah Noficandra, Pamungkas Bagus Satriyo ORCID, Dwi Aris Agung Nugrahaningsih ORCID
Adv Pharm Bull. doi: 10.34172/apb.45269 | Published on: 2026 May 23
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Review Article

Inhalable Nanomedicines for Chronic Obstructive Pulmonary Disease: Recent Developments and Translational Barriers
Ahmad Ainurofiq* ORCID, Elizabeth Agrindha Rosalin ORCID, Mayra Shafwa Istiyono ORCID, Natasya Anggira Maharani ORCID, Ryan Fauzy ORCID, Salma Nurhalizah Sugiharti ORCID, Yuliana Fania Safa ORCID
Adv Pharm Bull. doi: 10.34172/apb.46836 | Published on: 2026 May 23
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Review Article

Epigenetic Regulation of Cell Cycle Control in Colorectal Cancer: Molecular Mechanisms and Therapeutic Perspectives
Srinivasa B* ORCID, Devika P Jeeragyal ORCID, Kiran velukuri ORCID, Amarnath Reganti ORCID, Vaheedha S ORCID, Vinodhkumar Ramalingam ORCID, Rajasekhar Sreerama ORCID, Neelima Grandhe ORCID, Praveen hoogar ORCID
Adv Pharm Bull. doi: 10.34172/apb.47190 | Published on: 2026 May 23
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Research Article

Fluticasone Propionate-loaded Black Cumin Oil NLCs with Dual Deposition/Permeation Capabilities for Enhanced Psoriasis Management
Mohamed Ashraf ORCID, Hossam S. El-Sawy* ORCID, Ghada M El Zaafarany ORCID, Mona M. A. Abdel-Mottaleb* ORCID
Adv Pharm Bull. doi: 10.34172/apb.47080 | Published on: 2026 May 19
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Letter to Editor

Circulating Exosomal Cargoes and Platelet-Derived Factors May Contribute to Organ Failure in Sepsis

Muhammad Esa* ORCID, Sunisa Kaewpaiboon, Tawseef Ahmad, Muhammad Khan, Asad Ur Rahman*, Teerapol Srichana* ORCID
Adv Pharm Bull. doi: 10.34172/apb.47033 | Published on: 2026 May 19
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Letter to Editor

miR-34a in PFIC: Hypothesized Links to Dyslipidemia and Liver Regeneration
AMR AHMED EL-ARABEY* ORCID, Kapil K. Upadhyay
Adv Pharm Bull. doi: 10.34172/apb.46776 | Published on: 2026 May 19
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Research Article

Design and evaluation of a chalcone-based dimeric scaffold targeting amyloid-beta plaques for early detection of Alzheimer's disease: synthesis, radiolabeling, in vivo studies, and integrated molecular docking and dynamics simulation

Zahra Ghiamaty ORCID, Mehdi Akhlaghi* ORCID, Safura Jokar* ORCID, Hooman Hafezi, Omid Bavi, Mohammad Sharifzadeh, Omid Sabzevari, Mehdi Shafiee Ardestani, Tahereh Ghorbandaeipour, Mahboobeh Asadi, Mahshid Kiani, Sara Roustaei, Fatemeh Ebrahimi, Davood Beiki* ORCID
Adv Pharm Bull. doi: 10.34172/apb.46659 | Published on: 2026 May 19
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Research Article

Neurogenic Effect of Hypoxia-Conditioned UC-MSC Secretome from Macaca fascicularis in an In Vitro Stroke Model
Gita Serafika Shannon ORCID, Amarila Malik* ORCID, Ratih Rinendyaputri* ORCID, Sela Septima Mariya ORCID, Sunarno Sunarno ORCID, Rachmawati Noverina, Putri Retno Intan ORCID, Wireni Ayuningtyas, Fathul Huda ORCID, Ahmad Faried ORCID
Adv Pharm Bull. doi: 10.34172/apb.46137 | Published on: 2026 May 19
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Research Article

Optimization, ex-vivo penetration and in-vivo evaluation of PEGylated nanostructured lipid carriers of olmesartan medoxomil to enhance transdermal delivery
rofida albash* ORCID, Aly A. Abdelbary, Hanan refai, mohamed nabarawi
Adv Pharm Bull. doi: 10.34172/apb.46458 | Published on: 2026 May 19
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Letter to Editor

Beyond COX Inhibition: The Critical Role of the NF-κB Pathway in the Future of Anti-inflammatory Drugs
Ian Jhemes Oliveira Sousa* ORCID, Kerolayne de Melo Nogueira ORCID
Adv Pharm Bull. doi: 10.34172/apb.46607 | Published on: 2026 May 19
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Review Article

Electrospun Nanofibers for Dental Regeneration Therapy: Advancements and Perspectives
Pritha Dalapati ORCID, Vanshita Vanshita ORCID, Inderbir Singh* ORCID
Adv Pharm Bull. doi: 10.34172/apb.46505 | Published on: 2026 May 19
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Review Article

Chemical Design and Therapeutic Efficacy of HBsAg-Based Nanovaccines for Hepatitis B Virus Clearance: A Preclinical and Clinical Systematic Review
Hasti Nequi Marnani ORCID, Tahereh Zadeh Mehrizi* ORCID, Babak Eshrati, Mehdi Shafiee Ardestani, Nazanin Ajdary, Mohammad Vodjgani, Nariman Mosaffa
Adv Pharm Bull. doi: 10.34172/apb.45985 | Published on: 2026 May 19
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Research Article

Fish Skin-Derived Acellular Matrix with pH-Modulating Nanogels for Wound Healing
Hanieh Mahdiani ORCID, Faegheh Yazdani, Haleh Bakhshandeh, Hossein Aminianfar, Nazanin Samiei, Sholeh Maslehat, Amir Amanzadeh, Mahsa Khoramipour, Shahram Azari, Mohammad Ali Shokrgozar* ORCID, Rassoul Dinarvand* ORCID
Adv Pharm Bull. doi: 10.34172/apb.46166 | Published on: 2026 May 10
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Mini Review

Next-Generation Targeted Molecular Therapies in Immune-Mediated Inflammatory Diseases
Mostafa Akbarzadeh-Khiavi ORCID, Amir-Hossein Olfati, Azam Safary* ORCID
Adv Pharm Bull. doi: 10.34172/apb.46844 | Published on: 2026 May 10
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Letter to Editor

Exosome derived miRNA: a promising modality in the treatment of spinal cord injury and peripheral neuropathy
Aminath Efa Ibrahim ORCID, Kannan Subbaram* ORCID, Razana Faiz ORCID, Sheeza Ali ORCID, Queen Alice Arul ORCID
Adv Pharm Bull. doi: 10.34172/apb.46604 | Published on: 2026 May 10
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Letter to Editor

Long acting and highly effective pre-exposure prophylaxis (PrEP) using injectable lenacapavir (LEN) for HIV infection
Mariyam Niusha Naseer ORCID, Fathimath Ina Shareef ORCID, Ismail Junaih Shareef ORCID, Kannan Subbaram* ORCID, Razana Faiz ORCID, Sheeza Ali ORCID, Queen Alice Arul ORCID
Adv Pharm Bull. doi: 10.34172/apb.46524 | Published on: 2026 May 10
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Research Article

ACKR3 upregulation under hyperglycemia associates with endothelial dysfunction
Seyedeh Zohreh Azarshin ORCID, Zahra Abedi Kich ORCID, Shahram Rabbani ORCID, Mohammad Ali Boroumand ORCID, Mousa Golalizadeh Lahi ORCID, Mehrdad Behmanesh* ORCID
Adv Pharm Bull. doi: 10.34172/apb.46517 | Published on: 2026 May 10
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Research Article

ALA nanoemulsion prepared by microfluidic for ocular delivery: In-vitro and in-vivo studies
Javad Behmadi ORCID, Amiremad Kheirieh, Asma Mahmoudi, Mojtaba Abrishami, Seyed Ali Mousavi Shaegh, Amirhossein Abbasi, Bizhan Malaekeh-Nikouei* ORCID
Adv Pharm Bull. doi: 10.34172/apb.46273 | Published on: 2026 May 09
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Review Article

Nanotechnology-based drug delivery for Parkinson’s Disease: A review on strategies, efficacy and translational hurdles
Meghas Hari ORCID, Abhirami Subramony ORCID, Deepak Dwivedi, Reshmi S Krishnan, Aswin Damodaran, Sreeja C Nair* ORCID
Adv Pharm Bull. doi: 10.34172/apb.46162 | Published on: 2026 May 09
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Research Article

Smart Delivery of Resveratrol to Glioblastoma Cells Using Hybrid Nanoparticles: Cytotoxic, Uptake, and Pharmacokinetic Insights
SWATI DEVENDRA RAYSING* ORCID, Ashish Prakash Gorle ORCID
Adv Pharm Bull. doi: 10.34172/apb.46117 | Published on: 2026 May 09
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Research Article

PpSP42 and LmSTI1-PpSP42 Recombinant Proteins from Phlebotomus papatasi and Leishmania major Confer Protection against Leishmania major Infection in BALB/c mice
Fariborz Bahrami ORCID, Touraj Miandoabi ORCID, Vahideh Moein Vaziri ORCID, Farhad Riazi-Rad ORCID, Soheila Ajdary* ORCID
Adv Pharm Bull. doi: 10.34172/apb.45925 | Published on: 2026 May 09
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Review Article

GAS5 in Colorectal Cancer: A Multifaceted Long Non-Coding RNA in Tumor Suppression, Prognosis and Therapeutic Targeting
Jiaxian Ong ORCID, Sharanya Sritharan, Amar Harris Bin Arifin, Baskaran Gunasekaran*, Rhun Yian Koh, Nurulamin Abu Bakar, Shamala Salvamani* ORCID
Adv Pharm Bull. doi: 10.34172/apb.025.45936 | Published on: 2025 Dec 21
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