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Adv Pharm Bull. 2021;11(4): 595-600. doi: 10.34172/apb.2021.069
PMID: 34888206        PMCID: PMC8642806

Review Article

Ligament/Tendon Culture under Hypoxic Conditions: A Systematic Review

Sholahuddin Rhatomy 1 * ORCID, Dwikora Novembri Utomo 2, Cita Rosita Sigit Prakoeswa 3, Fedik Abdul Rantam 4,5, Heri Suroto 2, Ferdiansyah Mahyudin 2

Cited by CrossRef: 5


1- Shahid H, Morya V, Oh J, Kim J, Noh K. Hypoxia-Inducible Factor and Oxidative Stress in Tendon Degeneration: A Molecular Perspective. Antioxidants. 2024;13(1):86 [Crossref]
2- Kračun D, Görlach A, Snedeker J, Buschmann J. Reactive oxygen species in tendon injury and repair. Redox Biology. 2025;81:103568 [Crossref]
3- Paiva Barbosa V, Bastos Silveira B, Amorim dos Santos J, Monteiro M, Coletta R, De Luca Canto G, Stefani C, Guerra E. Critical appraisal tools used in systematic reviews of in vitro cell culture studies: A methodological study. Research Synthesis Methods. 2023;14(6):776 [Crossref]
4- Szczesny S, Corr D. Tendon cell and tissue culture: Perspectives and recommendations. Journal Orthopaedic Research. 2023;41(10):2093 [Crossref]
5- Adjei-Sowah E, Benoit D, Loiselle A. Drug Delivery Approaches to Improve Tendon Healing. Tissue Engineering Part B: Reviews. 2023;29(4):369 [Crossref]
6- Rhatomy S, Utomo D, Prakoeswa C, Suroto H, Tinduh D, Notobroto H, Arfian N, Rantam F, Mahyudin F. The optimum oxygen level in hypoxic culture conditions of ligament derived stem cells: experimental research. 2023;85(6):2689 [Crossref]
7- Luo Y, Liu L, Zhou X, Yang J, Tang M, Feng W, Du C, Liu X, Yang L, Liu F, Zhang L. IGF1-IGF1R signaling in tumor-associated macrophages regulates extracellular matrix organization in BRAF inhibitor-targeted melanoma. Mol Cell Biochem. 2026; [Crossref]
8- Heidenberger J, Hangel R, Reihs E, Strauss J, Liskova P, Alphonsus J, Brunner C, Döring K, Gerner I, Jenner F, Windhager R, Toegel S, Rothbauer M. The modulating role of uniaxial straining in the IL-1β and TGF-β mediated inflammatory response of human primary ligamentocytes. Front Bioeng Biotechnol. 2024;12 [Crossref]
9- Luo J, Wang Z, Lin R, Huang J, Tang C, Cai H, Fei Y, Ruan D, Wang X, Li P, Liu M, Yan R, Fan C, Wang C, Ye C, Ouyang H, Yin Z, Chen X, Shen W. Metabolic-pathway-based classification of tendinopathy reveals a precise therapeutic strategy targeting chondro-modulatory tenocytes. Bone Res. 2026;14(1) [Crossref]