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Adv Pharm Bull. 2018;8(4): 721-725. doi: 10.15171/apb.2018.081
PMID: 30607345        PMCID: PMC6311638

Short Communication

Overcoming Poor Solubility of Dimenhydrinate: Development, Optimization and Evaluation of Fast Dissolving Oral Film

Yuvraj Govindrao Jadhav 1, Upendra Chandrakant Galgatte 1 * ORCID, Pravin Digambar Chaudhari 1

Cited by CrossRef: 9


1- RIZK M, TEAIMA M, ABDELMONEM R, EL-NABARAWI M, ELHABAL S. BI-LAMINATED ORAL DISINTEGRATING FILM FOR SYMPTOMATIC TREATMENT OF VIRAL NASOPHARYNGITIS: FORMULATION, CHARACTERIZATION, TASTE MASKING, AND STABILITY STUDIES. Int J App Pharm. 2024;:267 [Crossref]
2- Salama A, Hamed Salama A, Hasanein Asfour M. Tannic acid coated nanosuspension for oral delivery of chrysin intended for anti-schizophrenic effect in mice. International Journal of Pharmaceutics. 2024;656:124085 [Crossref]
3- Taesotikul T, Pengnam S, Charoenying T, Pamornpathomkul B, Chaksmithanont P, Patrojanasophon P, Pornpitchanarong C. Dissolvable Face Mask with Liposomal Licorice Extract and Kojic Acid: An Innovative Approach for Skin Brightening. Cosmetics. 2026;13(1):21 [Crossref]
4- Lim S, Dafydd M, Ong J, Ord-McDermott L, Board-Davies E, Sands K, Williams D, Sloan A, Heard C. Mucoadhesive thin films for the simultaneous delivery of microbicide and anti-inflammatory drugs in the treatment of periodontal diseases. International Journal of Pharmaceutics. 2020;573:118860 [Crossref]
5- de Carvalho A, Paiva N, Demonari I, Duarte M, do Couto R, de Freitas O, Vicentini F. The Potential of Films as Transmucosal Drug Delivery Systems. Pharmaceutics. 2023;15(11):2583 [Crossref]
6- Aldawsari H, Badr-Eldin S. Enhanced pharmacokinetic performance of dapoxetine hydrochloride via the formulation of instantly-dissolving buccal films with acidic pH modifier and hydrophilic cyclodextrin: Factorial analysis, in vitro and in vivo assessment. Journal of Advanced Research. 2020;24:281 [Crossref]
7- Ma Y, Guan R, Gao S, Song W, Liu Y, Yang Y, Liu H. Designing orodispersible films containing everolimus for enhanced compliance and bioavailability. Expert Opinion on Drug Delivery. 2020;17(10):1499 [Crossref]
8- Bağcı K, Bağcı C, Uçar S, Tokpınar A, Arslan A, Balcıoğlu E, Yay A, Nisari M. Evaluation of the Effects of Dimenhydrinate at Different Dose Levels on Fetal Bone Development in Pregnant Rats: A Morphometric and Ultrastructural Study. Bratisl Med J. 2026; [Crossref]
9- Abla K, Mneimneh A, Allam A, Mehanna M. Application of Box-Behnken Design in the Preparation, Optimization, and In-Vivo Pharmacokinetic Evaluation of Oral Tadalafil-Loaded Niosomal Film. Pharmaceutics. 2023;15(1):173 [Crossref]
10- MOHANAN J, SUBRAMANIYAN G, KUTTALINGAM A, NARAYANASAMY D. IMPLEMENTING CENTRAL COMPOSITE DESIGN FOR THE DEVELOPMENT OF TACROLIMUS FILM FOR SUBLINGUAL ADMINISTRATION. Int J App Pharm. 2023;:35 [Crossref]
11- Osmari B, Medeiros G, da Rosa L, Funk N, de Souza P, Beck R, Cruz L. Fast-Dissolving Pullulan Film as a Solid Dosage Form for Sublingual Administration of Nifedipine-Loaded Nanocapsules. AAPS PharmSciTech. 2025;26(7) [Crossref]