Tabriz University of Medical Sciences Advanced Pharmaceutical Bulletin 2228-5881 3 2 2013 12 30 Characterization of Non-Terpenoids in Marrubium crassidens Boiss. Essential Oil 429 432 10.5681/apb.2013.069 EN Sanaz Hamedeyazdan Solmaz Asnaashari Fatemeh Fathiazad Journal Article 10.5681/apb.2013.069 2013 04 20 Purpose: Marrubium crassidens, a plant belonging to the family Lamiaceae, was studied for its volatile components present in the aerial parts of the plant during the flowering stage. Methods: The essential oil of the plant obtained through hydrodistillation of the dried plant material was assessed for its chemical composition by GC/MS and GC-FID analyses. Results: Twenty-five compounds were identified, which constituted 94.3% of the total oil composition. The major components were identified as, m-tolualdehyde (23.3%), acetophenone (15.8%), nonacosane (13.1%), docosane (7.2%), o-tolualdehyde (4.1%), β-caryophyllene (3.8%) and caryophyllene oxide (3.4%). Non-terpenoids with 75.7% were the most abundant components of the essential oil. Conclusion: Overall, M. crassidens essential oil revealed to include rather higher proportions of non-terpenoid compounds compared with other species of genus Marrubium.