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2025, Vol 15, No. 4

Advanced Pharmaceutical Bulletin (APB) is a peer-reviewed multidisciplinary open access journal, covering a wide range of integrative fields within Pharmaceutical sciences.
APB is the official journal of Drug Applied Research Center and Faculty of Pharmacy, published by TUOMS PRESS, Tabriz University of Medical Sciences.

Why Publish with APB?

Free of charge publication for all article types
Fast and constructive peer review
Simple and efficient online submission
Author-friendly review process
Rapid publication by means of running issue concept, which gives authors the benefit of 'No Waiting Time' for the officially accepted manuscripts
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Worldwide visibility of papers (Open Access Journal)

Original Research

1. Protective Effect of Prosopis cineraria Against N-Nitrosodiethylamine Induced Liver Tumor by Modulating Membrane Bound Enzymes and Glycoproteins

NAINA MOHAMED PAKKIR MAIDEEN*, RAVICHANDIRAN VELAYUTHAM, GOBINATH MANAVALAN

Adv Pharm Bull. 2012;2(2): 179-182. doi: 10.5681/apb.2012.027

PMCID: PMC3845991 PMID: 24312790 Scopus ID: 84875912104

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Original Research

2. Synthesis and Pharmacological Evaluation of Some New Pyrimidine Derivatives Containing 1, 2, 4-Triazole

Shantaram Gajanan Khanage*, S. Appala Raju, Popat Baban Mohite, Ramdas Bhanudas Pandhare

Adv Pharm Bull. 2012;2(2): 213-222. doi: 10.5681/apb.2012.033

PMCID: PMC3846002 PMID: 24312796 Scopus ID: 84874993523

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Original Research

3. Inhibitory and Cytotoxic Activities of Salvia Officinalis L. Extract on Human Lymphoma and Leukemia Cells by Induction of Apoptosis

fatemeh zare shahneh, Samira Valiyari, Behzad Baradaran*, Jalal Abdolali zadeh, Ali Bandehagh, Abass Azadmehr, Reza Hajiaghaee

Adv Pharm Bull. 2013;3(1): 51-55. doi: 10.5681/apb.2013.009

PMCID: PMC3846054 PMID: 24312812 Scopus ID: 84874967969

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Short Communication

4. In vitro Cytotoxic Activity of Four Plants Used in Persian Traditional Medicine

Fateme Zare Shahneh, Behzad Baradaran*, Mona Orangi, Fatemeh Zamani

Adv Pharm Bull. 2013;3(2): 453-455. doi: 10.5681/apb.2013.074

PMCID: PMC3848241 PMID: 24312877 Scopus ID: 84885715219

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Original Research

5. Antitumor Activity of Kielmeyera Coriacea Leaf Constituents in Experimental Melanoma, Tested in Vitro and in Vivo in Syngeneic Mice

Carlos Rogerio Figueiredo*, Alisson Leonardo Matsuo, Mariana Hiromi Massaoka, Natalia Girola, Ricardo Alexandre Azevedo, Aline Nogueira Rabaça, Camyla Fernandes Farias, Felipe Valença Pereira, Natalia Silva Matias, Luciana Pereira Silva, Elaine Guadelupe Rodrigues, Joao Henrique Guilardi Lago, Luiz Rodolpho Travassos, Regildo Márcio Gonçalves Silva

Adv Pharm Bull. 2014;4(5): 429-436. doi: 10.5681/apb.2014.063

PMCID: PMC4213781 PMID: 25364658 Scopus ID: 84906778194

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Research Article

6. Novel Doxorubicin Derivatives: Synthesis and Cytotoxicity Study in 2D and 3D in Vitro Models

Roman Akasov*, Maria Drozdova, Daria Zaytseva-Zotova, Maria Leko, Pavel Chelushkin, Annie Marc, Isabelle Chevalot, Sergey Burov, Natalia Klyachko, Thierry Vandamme, Elena Markvicheva

Adv Pharm Bull. 2017;7(4): 593-601. doi: 10.15171/apb.2017.071

PMCID: PMC5788214 PMID: 29399549 Scopus ID: 85043398199

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Research Article

7. In Vitro Assessment of Cytokine Expression Profile of MCF-7 Cells in Response to hWJ-MSCs Secretome

Mansoureh Mirabdollahi , Shaghayegh Haghjooy Javanmard , Hojjat Sadeghi-Aliabadi*

Adv Pharm Bull. 2019;9(4): 649-654. doi: 10.15171/apb.2019.075

PMCID: PMC6912178 PMID: 31857970 Scopus ID: 85075830066

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Research Article

8. Successful Application of Whole Cell Panning for Isolation of Phage Antibody Fragments Specific to Differentiated Gastric Cancer Cells

Sepideh Nikfarjam, Mohammad Reza Tohidkia* , Tayebeh Mehdipour, Ramin Soleimani, Ali Akbar Rahim Rahimi , Mohammad Nouri*

Adv Pharm Bull. 2019;9(4): 624-631. doi: 10.15171/apb.2019.072

PMCID: PMC6912189 PMID: 31857967 Scopus ID: 85075838868

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Original Research

9. Effects of Environmental Factors on Soluble Expression of a Humanized Anti-TNF-α scFv Antibody in Escherichia coli

Mohammad Sina, Davoud Farajzadeh, Siavoush Dastmalchi*

Adv Pharm Bull. 2015;5(4): 455-461. doi: 10.15171/apb.2015.062

PMCID: PMC4729350 PMID: 26819916 Scopus ID: 84949635419

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Review Article

10. Current Biochemical Applications and Future Prospects of Chlorotoxin in Cancer Diagnostics and Therapeutics

Sbonelo Khanyile , Priscilla Masamba , Babatunji Emmanuel Oyinloye , Londiwe Simphiwe Mbatha, Abidemi Paul Kappo*

Adv Pharm Bull. 2019;9(4): 510-520. doi: 10.15171/apb.2019.061

PMCID: PMC6912174 PMID: 31857956 Scopus ID: 85075838438

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Review Article

11. Tumor-Associated Macrophages: Protumoral Macrophages in Inflammatory Tumor Microenvironment

Somaiyeh Malekghasemi , Jafar Majidi, Amir Baghbanzadeh, Jalal Abdolalizadeh, Behzad Baradaran* , Leili Aghebati-Maleki*

Adv Pharm Bull. 2020;10(4): 556-565. doi: 10.34172/apb.2020.066

PMCID: PMC7539304 PMID: 33062602 Scopus ID: 85090455936

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Abstracting and Indexing

1. Protective Effect of Prosopis cineraria Against N-Nitrosodiethylamine Induced Liver Tumor by Modulating Membrane Bound Enzymes and Glycoproteins

2. Synthesis and Pharmacological Evaluation of Some New Pyrimidine Derivatives Containing 1, 2, 4-Triazole

3. Inhibitory and Cytotoxic Activities of Salvia Officinalis L. Extract on Human Lymphoma and Leukemia Cells by Induction of Apoptosis

4. In vitro Cytotoxic Activity of Four Plants Used in Persian Traditional Medicine

5. Antitumor Activity of Kielmeyera Coriacea Leaf Constituents in Experimental Melanoma, Tested in Vitro and in Vivo in Syngeneic Mice

6. Novel Doxorubicin Derivatives: Synthesis and Cytotoxicity Study in 2D and 3D in Vitro Models

7. In Vitro Assessment of Cytokine Expression Profile of MCF-7 Cells in Response to hWJ-MSCs Secretome

8. ­­­Successful Application of Whole Cell Panning for Isolation of Phage Antibody Fragments Specific to Differentiated Gastric Cancer Cells

9. Effects of Environmental Factors on Soluble Expression of a Humanized Anti-TNF-α scFv Antibody in Escherichia coli

10. Current Biochemical Applications and Future Prospects of Chlorotoxin in Cancer Diagnostics and Therapeutics

11. Tumor-Associated Macrophages: Protumoral Macrophages in Inflammatory Tumor Microenvironment

12. Restoring of miR-193a-5p Sensitizes Breast Cancer Cells to Paclitaxel through P53 Pathway

13. Bidirectional and Opposite Effects of Naïve Mesenchymal Stem Cells on Tumor Growth and Progression

14. Modulatory Effect of Rutin on the Antitumor Activity and Genotoxicity of Cisplatin in Tumor-Bearing Mice

15. Immunohistochemical Profile of Uterine Leiomyoma With Bizarre Nuclei; Comparison With Conventional Leiomyoma, Smooth Muscle Tumors of Uncertain Malignant Potential and Leiomyosarcoma

16. Co-Administration of Vadimezan and Recombinant Coagulase-NGR Inhibits Growth of Melanoma Tumor in Mice

17. Anti-tumor Effect of Quercetin Loaded Chitosan Nanoparticles on Induced Colon Cancer in Wistar Rats

18. Tumor-Specific Growth Factor (TSGF): A Futuristic Tumor Biomarker in Early Diagnosis of Cancer

19. CAR T Cells: Cancer Cell Surface Receptors Are the Target for Cancer Therapy

20. Anti-tumor Effects of Cisplatin Synergist in Combined Treatment with Clostridium novyi-NT Spores Against Hypoxic Microenvironments in a Mouse Model of Cervical Cancer Caused by TC-1 Cell Line

21. Drug Delivery of Solid Lipid Nanoparticles (SLNs) and Nanostructured Lipid Carriers (NLCs) to Target Brain Tumors

22. Exploring the Interplay between the Warburg Effect and Glucolipotoxicity in Cancer Development: A Novel Perspective on Cancer Etiology

23. Liposome-Fe3 O4-Doxorubicin Mediated Treatment of Melanoma Tumors

24. Dual-stage Acting Dendrimeric Nanoparticle for Deepened Chemotherapeutic Drug Delivery to Tumor Cells

25. Assessment of the Effect of Infliximab on Immunomodulation Properties of Mesenchymal Stem Cells In Vitro

26. PI3K Signaling Pathway Inhibitor Affects Myeloma Cells in a Culture-Dependent Manner

27. A Systematic Study on Long-acting Nanobubbles: Current Advancement and Prospects on Theranostic Properties

28. An Overview on Lipid Nanocapsules: Exploring the Role in Precision Cancer Treatment and Lymphatic Drug Distribution

29. Anti-Inflammatory Potency of Human Wharton’s Jelly Mesenchymal Stem Cell-Derived Exosomes on L2 Cell Line Induced by Lipopolysaccharides

30. Radachlorin-Containing Microparticles for Photodynamic Therapy

31. PTEN and p53 Combined Gene Therapy Promote Apoptosis and Chemosensitivity to Oxaliplatin in Colorectal Cancer: An In Vitro Study

32. Mebendazole-Treated Human Monocyte-Derived Dendritic Cells Represent Promoted Immunogenic Phenotype with Augmented Expression of Inflammatory Markers

33. Tumor Microenvironment Responsive TPZ-Loaded Core-Shell Polymeric Nanoparticles for Selective Cancer Bioreductive Therapy

34. Monoclonal Antibodies-Anchored Quantum Dots-Based Delivery Strategies for Glioblastoma Treatment: Challenges and Applications

35. A Newly Developed TGF-Β-Responsive CAR T Cell for Enhanced Proliferation and Cytokine Secretion

8. Successful Application of Whole Cell Panning for Isolation of Phage Antibody Fragments Specific to Differentiated Gastric Cancer Cells